FtA: Systems

So I think I've got a good idea of what the world looks like, and I know the direction I want to take the game, and the feel I want to give it, so now it's time for the number crunching.

I guess the easy way to go is to hang this on the d20 system, and add some custom charts for what I'm looking for.  It's simple, reasonably intuitive, and lots of people use it.  It will eliminate at least one roadblock that would prevent people from picking it up - that they don't want to learn a new system. 

But there's a part of me that's saying, if you're going to create a game, why stop halfway? 

The current trend in RPGs seems to be "rules lite", and I like that - I don't want someone to have to devote a weekend just to learning how to play the game.  If I"m going to go heavy on something, it should be setting and background.

I always liked White Wolf's system of dice pools set against a difficulty number.  It simple and intuitive, easy to pick up and was integrated perfectly with their background. 

There's the One-Roll Engine which uses d10 rolls, and successes are based on the number of matched pairs that come up.

Hell, Nuomenon, the weirdest rpg ever invented uses dominos!

So I guess I'm looking to come up with a system that requires as few charts as possible, but is easy to learn, and allows me to tie it to the setting as much as possible.

I'll be thinking hard on this one.